COMPARISONOF TWO DRUG REGIMENS IN TREATMENT OF RV FAILURE Page No: 3727-3731

Hani Harati and Fatemeh Firouzi

Keywords: CHF, COPD, carvedilol, right ventricular failure, right ventricular function

Abstract: Heart failure is one of the most common heart diseases with high rates of cardiovascular mortality and morbidity. Beta blockers are considered treat these patients to reduce mortality and improve right ventricular function and symptoms. Due to the increasing prevalence of this disease in the country, this study compared to determine the effect of carvedilol was performed on drugs right ventricular function Method:This clinical trial study was performed on 60patients with right ventricular failure. In this study, only standard therapy control group patients received the underlying disease in addition carvedilol to standard treatment group. And at the end of the second and sixth months in both groups, right ventricular failure indices were evaluated with echocardiography. And then data were compared using statistical software SPSS. Mean age61.8±9.0years. Our results showed that administration of carvedilol reduced the second month Tr severity is significant (p<0.001) and continue taking it until the sixth month in addition to reducing Tr, significant decreases are also Rvmpi. (p<0.001). But compared Taps index and right ventricular dilatation in the carvedilol group differences with the placebo group showed no significant (p>0.05). Based on present study findings in patients with right ventricular failure, patients prescribed carvedilol is improves symptoms of right ventricular function



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