GS George, AA Uwakwe and F Ogbotobo
Keywords: Micronutrients, blood sample, type 1 diabetic patients
Abstract: To investigate the relationship of micronutrients concentration in Type 1 Diabetic Patients and how their interactions affect the homeostasis in this hyperglycemic state, we evaluated the concentration of calcium, magnesium, zinc and glucose. We observed a concomitant increase in calcium with raised glucose level while magnesium and zinc levels where decreased. Using only Samples with plasma glucose above threshold (>10.0mmol/L) the micronutrients were measured at time intervals of 0 to 30 mins, 60 mins, 120 minutes, 180 mins and 240 mins. It was observed that raised glucose induced significant (P< 0.05) elevation of calcium from 20.2 + 1.4 mmol/L to 60.4 + 21 mmol/L while reduction of magnesium and zinc were in the order 180 + 7 to 58.4 + 3 ?mol/L and 15.4 + 0.5 to 4.3 + 0.4 ?mol/L respectively. We conclude that variations in concentration of micronutrients may elicit clinical expression of common abnormal homeostatic environment expressed partly by the reduced levels of magnesium and zinc that complicates the diabetic process
[View Complete Article]